Species Codes

Code Species
D Dog
H Hamster
M Mouse
N Prosimian
P Monkey
R Rat

Methods for NCI studies in Nonhuman Primates

The NCI Laboratory of Chemical Pathology conducted a 36-year project (1961-1997) on lifetime carcinogenesis studies in cynomolgus and rhesus monkeys. The CPDB includes lifetable analyses on 25 chemicals.

Some of the inclusion rules of the CPDB have been relaxed in order to include these monkey experiments. The following methodology has been adopted:


  1. Adamson, R. H., and Sieber, S. M. Chemical carcinogenesis studies in nonhuman primates. In: Organ and Species Specificity in Chemical Carcinogenesis. (R. Langenbach S. Nesnow, and J. M. Rice, Eds.), Plenum Press, New York and London, 1982, pp. 129-156.
  2. Adamson, R. H., Takayama, S., Sugimura, T., and Thorgeirsson, U. P. Induction of hepatocellular carcinoma in nonhuman primates by food mutagen 2-amino-3-methylimidazo[4,5-f]quinoline. Environ. Health Perspect. 102: 190-193(1994).
  3. Dalgard, D. W. Induction, Biological Markers and Therapy of Tumors in Primates. National Cancer Institute Final Report of Contract No. N01-CP-40510, Vienna, VA, Corning Hazelton Laboratory Study No. 421-166, Reporting period: July 1, 1994-March 31, 1997.
  4. Thorgeirsson, U. P., Dalgard, D. W., Reeves, J., and Adamson, R. H. Tumor incidence in a chemical carcinogenesis study in nonhuman primates. Regul. Toxicol. Pharmacol. 19: 130-151(1994).

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